Restless Legs Syndrome - Market Insights, Epidemiology, and Market Forecast


 

About Restless Legs Syndrome Market Report

In most cases, the cause of RLS is unknown (called primary RLS). However, RLS has a genetic component and can be found in families where the onset of symptoms is before age 40. Specific gene variants have been associated with RLS. Restless legs syndrome (RLS) is known to occur secondary to various medical conditions such as iron deficiency, pregnancy, end-stage renal disease, and neuropathy. Sleep deprivation and other sleep conditions like sleep apnea also may aggravate or trigger symptoms in some people. Reducing or completely eliminating these factors may relieve symptoms.

It is estimated that up to 7-10 percent of the U.S. population may have Restless Legs Syndrome. It may begin at any age. Many individuals who are severely affected are middle-aged or older, and the symptoms typically become more frequent and last longer with age. More than 80 percent of people with RLS also experience periodic limb movement of sleep (PLMS).

A total of 16, 202 adults (aged ≥18 years) were interviewed using validated diagnostic questions to determine the presence, frequency, and severity of RLS symptoms; respondents reporting RLS symptoms were asked about medical diagnoses and the impact of the disorder and completed the Short Form-36 Health Survey (SF-36). In all, 15,391 fully completed questionnaires were obtained; RLS symptoms of any frequency were reported by 1114 (7.2%). This study concluded that clinically significant RLS is common (prevalence, 2.7%), is underdiagnosed, and significantly affects sleep and quality of life.

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