The exact causes of SLL/CLL are still unknown. It has been
stated that SLL is not infectious and cannot be passed on to other people. Few
factors, however increase the risk for SLL, which includes working on a farm or
as a hair stylist or any other disease that weak immune system.
CLL can be diagnosed on a blood test. SLL is usually
diagnosed by taking a sample of cells from a swollen lymph node to look at
under a microscope. This is called a lymph node biopsy. Depending upon
patient’s condition, treatments for SLL/CLL may include the following:
Chemotherapy, Targeted therapy, Steroids, Stem cell transplants and Radiotherapy.
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Previously, SLL and CLL were through to be different
diseases, but are today regarded as different manifestations of the same
disease, referred to collectively as CLL/SLL. Till now, the exact causes of
SLL/CLL are unidentified with doctors and researchers continually working to
understand the exact mechanisms that cause this disease. Two things which have
been stated by several studies and organizations is that like other cancers, it
is not infectious and cannot be passed on to other people. It is more common as
people get older. SLL/CLL affects adults and is usually diagnosed in people
aged over 60 years. The median age of people at diagnosis is 65 years and is
more common in men than in women. The disease may have a familial link (i.e.,
‘run’ in families), but has no clear inherited basis, and the risk of other
family members developing SLL/CLL is very small.
When someone suffers from CLL/SLL the overall outlook
depends on the stage of the cancer and other variables. Because of the way that
blood and bone marrow are involved in CLL, the staging systems for CLL are
different from those used for other types of NHL, including SLL. Patients with
CLL are staged using either the Rai staging system (mostly used in US) or the
Binet classification system (more widely in Europe). CLL/SLL are slow growing
cancer which are not curable however, it is manageable with treatment. One of
the major unmet need is that CLL/SLL often comes back after it is treated. Most
people will need to go through a few rounds of treatment to keep their cancer
under control. Treatment aims to reduce the symptoms and keep the CLL/SLL under
control for as long as possible with as few side effects as possible.
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